Levels of Apolipoproteina-1, Apolipoprotein B, and Glucose of the Elderly, Exercising, and Non-Exercising Individuals in Nnewi, Nigeria Lipids and Glucose Levels of The Elderly, Actively and Non-Exercising Individuals

Abstract

Background: Cardiovascular disease causes death and disability. Objectives: To evaluate the serum levels of Apo A-1, Apo B, and glucose in the elderly, actively exercising and non-actively exercising individuals in Nnewi. Materials and methods: Ninety subjects recruited for the study were grouped into; Group A- Non-exercising, Group B Exercising, and Group C- Elderly Individuals aged 55 years and above. Blood sample was collected from the participants after 10-12 hours overnight fasting. Apolipoprotein A-1, Apolipoprotein B, and Glucose levels were determined spectrophotometrically. Their systemic (SBP), and diastolic blood pressures (DBP) Heights, and weights were measured. The questionnaire obtained their socio-demographic information. Data were analyzed using ANOVA, Bonferroni Post Hoc Test, and Pearson r correlation. Result: A significantly higher difference existed in the mean serum value of glucose in the Elderly (6.60 ± 1.50) and exercising (5.89 ± 0.82) compared with the Non-exercising (5.40 ± 0.48)( p<0.05). A significantly higher difference was seen in the mean SBP, DBP, and BMI levels of the Elderly compared with the non-exercising (p≤0.05). However, the exercising had significantly lower mean SBP, DBP, and BMI values than the Non-exercising group (p≤0.05). A strong positive correlation was observed between Apo B vs Apo A-1 in the exercising, and Non-exercising groups, while a weak negative correlation existed between BMI and Apo A-1 in the actively exercising. Conclusion: The significant differences observed in the parameters measured were not clinically significant.